I think of a discussion on BBC radio 4, first broadcast 5th November 1998 (http://www.bbc.co.uk/programmes/p005457h)
between the physicist and popular-science author John Gribbin and MM.
In this discussion Dr Gribbin confidently asserts that the human-social activity "football" (Mary Midgley's example) can be fully and meaningfully explained through a complete physical account of all that is happening in a football match, which would include the account of the interaction of particles forming the brains of the players, referee and spectators.
I recommend listening to the discussion to get a proper flavour of the absence of self-reflection that prevents Dr Gribbin from seeing the grounds for the criticisms that are put to him by MM.
Here a quote from the auto-biography of Bryan Magee (p.426/7), again from the chapter on Schopenhauer, that echoes MM's approach.
"The metaphysical visions of philosophers are not empirically verifiable, and this us as true of those of the empiricists as of any if the others. When Locke, like Descartes, presents us with a vision of the universe as a vast cosmic machine made up of lesser machines, all of them subject to the same scientific laws, this is not a scientific theory that observers can investigate and test, it is a vision of how things are; yet it will have a thousand practical influences on whoever accepts it. And when, by contrast, Schelling comes along and says that reality us not so much like a machine as like a single great big living organism, and is therefore better understood as a quasi-organic developmental process rather than as something mechanical, and that in the highest products of the human mind this process achieves an understanding of itself, there are no crucial experiments by means of which scientific-minded observers can adjudicate between this view and Locke's to decide which of the two, if either, is 'true'. However, to conclude from this that such world outlooks are nothing but words, and therefore fanciful, a lot of nonsense - a load, really, of meaningless metaphysics - is a profound mistake. It is those metaphysical visions that give rise to our research programmes, as they did in the case of both Plato and, two thousand years later, empirical scientists."